Structural, enzymatic and pharmacological profiles of AplTX-II - A basic sPLA2 (D49) isolated from the Agkistrodon piscivorus leucostoma snake venom

A basic sPLA2 (D49) from the venom of snake Agkistrodon piscivorus leucostoma (AplTX-II) was isolated, purified and characterized. We determined the enzymatic and pharmacological profiles of this toxin. AplTX-II was isolated with a high level of purity through reverse phase chromatography and molecu...

• Hlavní autor: Resende, Letícia M. (author)
• Další autoři: de Almeida, José R. (author), Guaraca Medina, Tatiana Alejandra (author), F.Viegas, Matilde (author), Soaresc, Andreimar M. (author), Ramos, Maria J. (author), Fernandes, Pedro A. (author), Marangoni, Sergio (author), da Silva, Saulo L. (author)
• Médium: article
• Vydáno: 2021
• Témata: Basic sPLA2 D49; Agkistrodon piscivorus leuscostoma; Molecular modeling; NOBA (4-nitro-3-octanoyloxy benzoic acid)
• On-line přístup: https://doi.org/10.1016/j.ijbiomac.2021.01.187.; http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/425