Structural, enzymatic and pharmacological profiles of AplTX-II - A basic sPLA2 (D49) isolated from the Agkistrodon piscivorus leucostoma snake venom

Structural, enzymatic and pharmacological profiles of AplTX-II - A basic sPLA2 (D49) isolated from the Agkistrodon piscivorus leucostoma snake venom

A basic sPLA2 (D49) from the venom of snake Agkistrodon piscivorus leucostoma (AplTX-II) was isolated, purified and characterized. We determined the enzymatic and pharmacological profiles of this toxin. AplTX-II was isolated with a high level of purity through reverse phase chromatography and molecu...

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Bibliographic Details
Main Author: Resende, Letícia M. (author)
Other Authors: de Almeida, José R. (author), Guaraca Medina, Tatiana Alejandra (author), F.Viegas, Matilde (author), Soaresc, Andreimar M. (author), Ramos, Maria J. (author), Fernandes, Pedro A. (author), Marangoni, Sergio (author), da Silva, Saulo L. (author)
Format: article
Published: 2021
Subjects:
Basic sPLA2 D49
Agkistrodon piscivorus leuscostoma
Molecular modeling
NOBA (4-nitro-3-octanoyloxy benzoic acid)
Online Access:https://doi.org/10.1016/j.ijbiomac.2021.01.187.
http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/425
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