Structure−Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes

Pentacyclic triterpenes may be active agentsand provide a rich natural resource of promising compoundsfor drug development. The inhibitory activities of 29 naturaloleanane and ursane pentacyclic triterpenes were evaluatedagainst four major enzymes involved in the inflammatoryprocess: 5-LOX, 15-LOX-2...

• 主要作者: Quynh Vo, Nhu Ngoc (author)
• 其他作者: Nomura, Yuhta (author), Muranaka, Toshiya (author), Fukushima, Ery Odette (author)
• 格式: article
• 出版: 2019
• 主題: Entacyclic; Triterpenoids; Inhibitors Enzymes; Cyclooxygenase and Lipoxygenase
• 在線閱讀: http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/328; https://doi.org/10.1021/acs.jnatprod.9b00538