Structure−Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes

Pentacyclic triterpenes may be active agentsand provide a rich natural resource of promising compoundsfor drug development. The inhibitory activities of 29 naturaloleanane and ursane pentacyclic triterpenes were evaluatedagainst four major enzymes involved in the inflammatoryprocess: 5-LOX, 15-LOX-2...

• Tác giả chính: Quynh Vo, Nhu Ngoc (author)
• Tác giả khác: Nomura, Yuhta (author), Muranaka, Toshiya (author), Fukushima, Ery Odette (author)
• Định dạng: article
• Được phát hành: 2019
• Những chủ đề: Entacyclic; Triterpenoids; Inhibitors Enzymes; Cyclooxygenase and Lipoxygenase
• Truy cập trực tuyến: http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/328; https://doi.org/10.1021/acs.jnatprod.9b00538