Structure−Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes

Structure−Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes

Pentacyclic triterpenes may be active agentsand provide a rich natural resource of promising compoundsfor drug development. The inhibitory activities of 29 naturaloleanane and ursane pentacyclic triterpenes were evaluatedagainst four major enzymes involved in the inflammatoryprocess: 5-LOX, 15-LOX-2...

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Bibliographic Details
Main Author: Quynh Vo, Nhu Ngoc (author)
Other Authors: Nomura, Yuhta (author), Muranaka, Toshiya (author), Fukushima, Ery Odette (author)
Format: article
Published: 2019
Subjects:
Entacyclic
Triterpenoids
Inhibitors Enzymes
Cyclooxygenase and Lipoxygenase
Online Access:http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/328
https://doi.org/10.1021/acs.jnatprod.9b00538
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