A novel synthetic peptide inspired on Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates

Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics are increasing, while alternative medicines are drying up, which urges the need to discover novel agents able to kill antibiotic-resistant bacteria. Lys49 phospholipase A2s (PLA2s) from snake venoms ar...

• Main Author: de Almeida, José R. (author)
• Other Authors: Mendes, Bruno (author), Lancellotti, Marcelo (author), Marangoni, Sergio (author), Vale, Nuno (author), Passos, Óscar (author), Ramos, María J. (author), Fernandes, Pedro A. (author), Gomes, Paula (author), da Silva, Saulo L. (author)
• Format: article
• Published: 2018
• Subjects: Antibacterial activity; Biomimetic peptide; Snake venom; Phospholipase A2
• Online Access: https://doi.org/10.1016/j.ejmech.2018.02.055; http://dspace.ikiam.edu.ec:8080/jspui/handle/RD_IKIAM/206