Inspiration from cruzioseptin-1: membranolytic analogue with improved antibacterial properties

Peptide engineering has gained attraction as a source of new cationicity-enhanced analogues with high potential for the design of next-generation antibiotics. In this context, cruzioseptin-1 (CZS-1), a peptide identified from Cruziohyla calcarifer, is recognized for its antimicrobial potency. Howeve...

• Hlavní autor: Bermúdez Puga, Sebastián Armando (author)
• Další autoři: Morán Marcillo, Giovanna (author), Espinosa de Los Monteros Silva, Nina (author), Naranjo, Renato E (author), Toscano, Fernanda (author), Vizuete, Karla (author), de Almeida, José R (author), Proaño Bolaños, Carolina (author), Torres Arias, Marbel (author)
• Médium: article
• Vydáno: 2023
• Témata: Antimicrobial peptides; Cruzioseptin.; Membranolytic effect; Rational design
• On-line přístup: https://doi.org/10.1007/s00726-022-03209-6; http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/646