Novel Kazal-type proteinase inhibitors from the skin secretion of the Splendid leaf frog, Cruziohyla calcarifer

Peptidase inhibitors have an important role controlling a variety of biological processes. Here, we employed a peptidomic approach including molecular cloning, tandem mass spectrometry and enzymatic assays to reveal 7 Kazal-type proteinase inhibitors (CCKPs) (18 variants) in the skin secretion of th...

• 1. Verfasser: Proaño Bolaños, Carolina (author)
• Weitere Verfasser: Li, Renjie (author), Zhou, Mei (author), Wang, Lei (author), Xi, Xinping (author), Tapia, Elicio E. (author), Coloma, Luis A. (author), Chen, Tianbao (author), Shaw, Chris (author)
• Format: article
• Veröffentlicht: 2017
• Schlagworte: Kazal-type proteinase inhibitors; Frog skin secretion; Peptidomic; Molecular cloning; Tandem mass spectrometry; Cruziohyla calcarifer
• Online Zugang: https://doi.org/10.1016/j.euprot.2017.02.001; http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/130