Novel Kazal-type proteinase inhibitors from the skin secretion of the Splendid leaf frog, Cruziohyla calcarifer

Novel Kazal-type proteinase inhibitors from the skin secretion of the Splendid leaf frog, Cruziohyla calcarifer

Peptidase inhibitors have an important role controlling a variety of biological processes. Here, we employed a peptidomic approach including molecular cloning, tandem mass spectrometry and enzymatic assays to reveal 7 Kazal-type proteinase inhibitors (CCKPs) (18 variants) in the skin secretion of th...

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Bibliographic Details
Main Author: Proaño Bolaños, Carolina (author)
Other Authors: Li, Renjie (author), Zhou, Mei (author), Wang, Lei (author), Xi, Xinping (author), Tapia, Elicio E. (author), Coloma, Luis A. (author), Chen, Tianbao (author), Shaw, Chris (author)
Format: article
Published: 2017
Subjects:
Kazal-type proteinase inhibitors
Frog skin secretion
Peptidomic
Molecular cloning
Tandem mass spectrometry
Cruziohyla calcarifer
Online Access:https://doi.org/10.1016/j.euprot.2017.02.001
http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/130
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