Anti-platelet aggregation activity of two novel acidic Asp49-phospholipases A2 from Bothrops brazili snake venom

Phospholipases A2 (PLA2s) are important enzymes present in snake venoms and are related to a wide spectrum of pharmacological effects, however the toxic potential and therapeutic effects of acidic isoforms have not been fully explored and understood. Due to this, the present study describes the isol...

• Main Author: Sobrinho, Juliana C. (author)
• Other Authors: Kayano, Anderson M. (author), Simões Silva, Rodrigo (author), Alfonso, Jorge (author), Gomez, Ana F. (author), Gomez, Maria C. (author), Zanchi, Fernando B. (author), Moura, Laura A. (author), Souza, Vivian R. (author), Fuly, André L. (author), de Oliveira, Eliandrede (author), da Silva, Saulo L. (author), de Almeida, José R. (author), Zuliani, Juliana P. (author), Soares, Andreimar M. (author)
• Format: article
• Published: 2018
• Subjects: Bothrops brazili; Snake venom; Acidic phospholipases A2; Anti-platelet aggregation activity
• Online Access: https://doi.org/10.1016/j.ijbiomac.2017.09.069; http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/172