Factores de riesgo asociados con el desarrollo de tuberculosis en pacientes con vih

Tuberculosis infection in HIV-positive patients is considered a significant pathological aggravator that worsens the prediction for vulnerable patients. The HIV virus modifies the immune system, facilitating the spread of Mycobacterium tuberculosis and predisposing the body to active tuberculosis. This study examines the risk factors associated with the development of tuberculosis (TB) in patients with HIV. The objective of this research was to determine risk factors to gain a more comprehensive and deep understanding of these causes and conditions. This study aims to determine the risk factors associated with the development of tuberculosis in HIV patients. A PECO question was structured using various Boolean operators such as OR and AND and a PRISMA-guided screening of information. In the systematic literature review, 35 articles were found, identifying a series of clinical, sociodemographic, and behavioral factors that increase the likelihood of developing tuberculosis in people with HIV. These factors include low resources and overcrowded conditions, whether in housing or confinement, extended use of corticosteroids, substance abuse (alcohol, tobacco, hallucinogens, among others), and inadequate medical care for the affected population. This study highlights the importance of public health factors related to issues such as adherence to antiretroviral therapy (ART) and treatment abandonment. Concludes, that it is necessary to improve access to ART through the creation of programs for the most vulnerable populations and provide greater attention to patients in low-income conditions, such as homeless migrants and prisoners.

• Main Author: Delgado Holguín, Ivonne Madelein (author)
• Format: masterThesis
• Language: spa
• Published: 2025
• Subjects: VIH; TUBERCULOSIS; FACTORES DE RIESGO; COINFECCIÓN; TRATAMIENTO ANTIRRETROVIRAL
• Online Access: https://dspace.uniandes.edu.ec/handle/123456789/19333