Pharmacological effects of PARP inhibitors on cancer and other diseases

Poly(ADP-ribosylation), a post-translational modification of proteins involved in DNA repair, replication, transcription and cell death, consists in the conversion of �-NAD + into ADP-ribose, and the further formation of polymers of variable length and structure bound to nuclear protein acceptors. P...

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Autore principale: Guaman Ortiz, L. (author)
Natura: article
Pubblicazione: 2011
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Accesso online:http://dspace.utpl.edu.ec/handle/123456789/19238
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