Pharmacological effects of PARP inhibitors on cancer and other diseases
Poly(ADP-ribosylation), a post-translational modification of proteins involved in DNA repair, replication, transcription and cell death, consists in the conversion of �-NAD + into ADP-ribose, and the further formation of polymers of variable length and structure bound to nuclear protein acceptors. P...
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| Format: | article |
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2011
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| Accés en línia: | http://dspace.utpl.edu.ec/handle/123456789/19238 |
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