Fishing potent tyrosinase inhibitors with new molecular docking protocol from natural products ocean

Melanin has an important biological role, although their overproduction and accumulation are associated with some diseases going from skin problems as melasma to Parkinson's disease. The overproduction of melanin is due to an increase in the number of melanocytes or melanogenic enzyme activ...

• Autor principal: Velastegui Gamboa, Camila Lissett (author)
• Formato: bachelorThesis
• Idioma: eng
• Publicado em: 2021
• Assuntos: Inhibidor de tirosinas; Acoplamiento molecular; Autodock-Vina; Modelos predictivos; SiLis-PREENZA Software; Cribado virtual; Productos naturales; Tyrosinase inhibitor; Molecular docking; Machine learning; Predictive model; Virtual screening; Natural product
• Acesso em linha: http://repositorio.yachaytech.edu.ec/handle/123456789/326