Synthesis and characterization of in vitro biologically active protein-polymer-based nanoparticulate formulations

Protein therapeutics is considered as an attractive and valuable strategy for treating an extensive list of difficult-to-treat diseases. However, its clinical effectiveness is diminished by the high lability of proteins in physiological environments. In particular, interferon α (IFNα) is a therapeut...

• Autore principale: Gancino Guevara, Marlon Alexander (author)
• Natura: bachelorThesis
• Lingua: eng
• Pubblicazione: 2020
• Soggetti: Protein therapeutics; Protein delivery; Protein formulation; Recombinant porcine interferon α; Chitosan nanoparticles; Ionotropic gelation; Antiviral activity; Terapéutica de proteínas; Administración de proteínas; Formulación de proteínas; Interferón α porcino recombinante; Nanopartículas de quitosano; Gelificación ionotrópica; Actividad antiviral
• Accesso online: http://repositorio.yachaytech.edu.ec/handle/123456789/189