Novel linker to bioconjugation based on tetrahydrothiadiazine-2-thione (thtt) scaffold

Cancer is one of the diseases with the highest mortality rate and whose treatments to mitigate it usually are so strong and invasive that they end up weakening the patient so that that cure can be as dangerous as the disease. From some time ago until today, to reduce the tolerance generated by the c...

• Main Author: Castillo Quijije, Danna Belén (author)
• Format: bachelorThesis
• Language: eng
• Published: 2019
• Subjects: Linker; Antibody-drug conjugate; Tetrahydrothiadiazin-2-thione; Acidolysis; Bioconjugation; Bovine serum albumin; Anti-alpha-tubulin; Enlazador; Conjugado anticuerpo-fármaco; Tetrahidrotiadiazin-2-tiona; Acidólisis; Bioconjugación; Albúmina de suero bovino; Anti-alfa-tubulina
• Online Access: http://repositorio.yachaytech.edu.ec/handle/123456789/78